Dr. Loraine earned her Ph.D. degree in Molecular and Cell Biology in 1996 and did postdoctoral work in bioinformatics at the Berkeley Drosophila Genome Project. Following her postdoc, she joined a bioinformatics software company that was later purchased by Affymetrix, a microarray company.
In 2004, she returned to academia to start a research program with two goals: (1) build and support visualization software for genomics, and (2) understand how alternative splicing affects gene function. She continues to be fascinated by technology and how IT innovations accelerate and shape scientific discovery.
- Publications, patent applications, and pre-prints from Google Scholar
- Presentations (from classes & talks) on SlideShare
- Software and data analysis code repositories on Bitbucket
- NIH biosketch: Loraine-Biosketch-Dec-2017 (PDF)
- Curriculum vitae: ALoraine-CV-Jan-2018 (PDF)
- Resume: ALoraine-Resume-May-2018 (PDF)
Ann Loraine’s home town is Austin, Texas. She attended high school at SF Austin High School and spent her senior year at Chiswick Community School in London. After winning a Dedman Merit Scholarship, she returned to Austin to attend the University of Texas at Austin, where she majored in zoology and Plan II, an honors liberal arts program.
After college she moved to the San Francisco Bay Area to attend graduate school at UC Berkeley. In 1996, she earned a Ph.D. degree in Molecular and Cell Biology. Around then, she became fascinated with using computers to do biology research. Instead of doing a traditional postdoc, she took time out to learn programming by taking computer science classes at UC Berkeley. She also worked part-time for the DNA Files, public radio documentaries on genetics.
In 1997 she joined the Berkeley Drosophila Genome Project, where she wrote visualization applets (in Java) for the project Web site. In 1999, she joined Neomorphic Software, a bioinformatics software company started by BDGP alumni Gregg Helt, Cyrus Harmon, and Martin Reese, also co-founder of personal genomics company Omicia. At Neomorphic, Ann helped write Annotation Station, a visualization and curation tool researchers at TIGR (now JCVI) used to annotate the first version of the Arabidopsis genome. (Ann wrote the Gene Editor part.)
When Affymetrix bought Neomorphic in 2001, Ann re-joined the new company as a Bioinformatics Scientist. At Affymetrix, she contributed to articles on probe set annotation (NetAffx), alternative splicing, and genome data visualization.
In 2004, Ann returned to academia as an assistant professor in
Biostatistics and Genetics at the University of Alabama at Birmingham. At UAB, she did research and taught in the Section on Statistical Genetics. In 2008, she moved UNC Charlotte to join the newly formed Dept. of Bioinformatics and Genomics.
Here’s is a photo of the team at Neomorphic:
Here is a photo of the Loraine Lab in 2014: